FibroScan vs Liver Biopsy: What’s the Difference?

FibroScan and liver biopsy both check liver health, but they work very differently. FibroScan is a painless scan that uses sound waves, while a biopsy removes a tiny piece of liver tissue with a needle. Most doctors now prefer FibroScan because it’s safer and faster.
What Is FibroScan?
FibroScan is a special ultrasound test. It checks liver stiffness and fat without needles. The test takes about 5-10 minutes.
A small device sits on your skin near your liver. It sends gentle sound waves through your body. The machine gives two scores: liver stiffness and fat content. You get results right away with no recovery time needed.
What Is a Liver Biopsy?
A liver biopsy removes a small tissue sample from your liver. Doctors look at it under a microscope to check for disease.
The doctor numbs your skin, then puts a thin needle through your belly into your liver. The whole process takes 20-30 minutes. Most people feel some pain where the needle went in. You must rest for 3-4 hours after the test.
Key Differences at a Glance
| Feature | FibroScan | Liver Biopsy |
| Pain Level | None | Some pain |
| Time Needed | 5-10 minutes | 20-30 minutes |
| Recovery | None | Several days |
| Risks | Very few | Bleeding possible |
| Results | Immediate | Takes days |
Which Test Should You Get?
Your doctor picks the right test based on what they need to find out.
Choose FibroScan when:
- Checking for fatty liver disease
- Monitoring liver health over time
- You need quick, safe results
Choose liver biopsy when:
- Doctors need very detailed information
- Other tests show unclear results
- FibroScan results don’t match other findings
For many people with chronic disease management needs, FibroScan offers a comfortable first step.
Final Thoughts
FibroScan is painless, fast, and safe for most people. Liver biopsy gives more detailed information but comes with some risks and recovery time.
Talk to your doctor about which test fits your needs. At Yorktown Health Vernon Hills Primary Care, our team can help you make the best choice for your health. Schedule an annual physical to discuss testing options.

